Panadol overview

Man sick

The world’s leading range for the treatment of symptoms of cold and flu

The Panadol Cold & Flu range contains clinically proven active ingredients to fight multiple symptoms*

* Align with LOC SmPC

Panadol – relief from cold and flu symptoms1-10

Sample icon

Cold symptoms relief

Panadol products relieve the eight most bothersome symptoms of colds and flu:fever, sinus congestion, headache, muscle pain, body pain, nasal congestion, sinus pain, and sore throat pain.1-10

Light bulb

Effective combination

Panadol products are powerful, multi-action, convenient, and well tolerated combinations that are suitable for active, busy patients, who need to stay alert.1-10

Tube icon

Strong scientific evidence

Multiple clinical studies, published in international, peer-reviewed journals, showed the strength of Panadol products for relieving cold and flu symptoms.3,5-10

Panadol – in-depth patient understanding

  • Cold symptoms are common and bothersome

    Nasal symptoms icon

    Control the most bothersome and frequent symptoms of colds and flu

    Cold and flu symptoms are frequent and bothersome. These symptoms include: fever (elevated body temperature), nasal congestion (a blocked nose), rhinorrhoea (a runny nose), sinus pressure and pain (headaches), sneezing (blowing your nose often), sore throat (pain in the pharynx), and body aches (pain all over the body). The Panadol range offers various options of clinically proven products, to relieve these symptoms.1-10

    Read more

  • Prevalence of the condition

    Are your patients experiencing cold and flu symptoms?

    Graph icon

    Between 5-10% of adults worldwide get a cold/flu every year.11

    Adult and children icon

    On average, adults get 4 to 6 colds per year, while children get 6 to 8 of them.12

  • Patients’ daily lives are impacted by cold and flu symptoms

    Cold and flu symptoms can have a major impact:

    Women coughing

    Impact on daily life

    52% of people stated that a cough/cold had a significant effect on their daily life.13

    Man at work

    Reduced productivity

    People reported a productivity decrease of 26%.13

    Women at home

    Decreased work/school attendance

    Nearly 50% of people reported missing work or school for 1-2 days.13

    Sleep icon

    Disturbed/poor sleep

    Total sleep time decreased by an average of 23 minutes.14

    Brain icon

    Performance reduction

    Reduced performance, mood, reaction time, and cognitive performance, was reported.13,15-17

Women drinking

The Panadol range is specially formulated for clinically proven relief from the symptoms of colds and flu1-10


Paracetamol is an over-the-counter drug used for pain relief and fever. It provides effective and sustained fever control, which starts to relieve fever in 30 minutes for up to 6 hours.3


Pseudoephedrine is a sympathomimetic drug that acts on the adrenergic receptors and causes vasoconstriction of the muscles lining the walls of small blood vessels in the nasal mucosa. By contracting the blood vessels, pseudoephedrine increases the patency of the airways and causes a decrease in the symptoms of nasal congestion.5,18

Phenylephrine hydrochloride

Phenylephrine is a sympathomimetic decongestant that has a potent vasoconstrictive effect on the capillaries in the nasal lining, which in turn leads to a reduction in the swelling of the nasal mucosa, thereby reducing congestion.6


Chlorpheniramine is a first-generation antihistamine used to relieve a runny nose and sneezing symptoms, to help patients sleep restfully.19


Guaifenesin is an expectorant that is suitable for the treatment of a wet cough, and is available in combination with paracetamol and phenylephrine, for short-term relief of the symptoms of colds and influenza.20-22


Caffeine is an analgesic adjuvant for paracetamol that increases mental alertness and improves wakefulness.23-25

Ascorbic acid

Ascorbic acid (Vitamin C) is an essential component of the human diet. It is included to supplement dietary intake of Vitamin C. This is particularly valuable in the early stages of acute viral infections, e.g., the common cold, as Vitamin C reserves may be low at this time and the appetite poor.27


Butamirate acts centrally to suppress coughs.29 It also has a non-specific anticholinergic effect, and a bronchospasmolytic effect that relieves sudden muscle constriction in the walls of the bronchioles. Together, these facilitate respiratory function.29-31

The Panadol range offers clinically proven solutions tailored to individual patient needs1–10

Panadol C&F Hot Liquid packshot

Panadol C&F Vapour Release

Panadol C&F Hot Liquid works as a soothing hot remedy for prompt relief from the symptoms of colds and flu, including headache, nasal congestion, sinus congestion, sinus pain, body aches, and fever.3,6,7,9,19,32,33

Key ingredients: Paracetamol 600mg, phenylephrine hydrochloride 10mg, and ascorbic acid 40mg.

Panadol C&F Day packshot

Panadol C&F Day

Panadol C&F Day provides powerful and effective relief against cold and flu symptoms, with caffeine to produce a synergistic effect with paracetamol.3,4,6,8-10,18-20,34-41

Key ingredients:Paracetamol 50mg, phenylephrine 5mg, and caffeine 25mg.

Panadol C&F Night/Nasal packshot

Panadol C&F Night

Panadol C&F Night/Nasal is designed to relieve fever, aches, and the pains associated with colds and flu, which cause difficulty in getting to sleep.4,6,19,28,35-37

Key ingredients: Paracetamol 500mg, pseudoephedrine hydrochloride 30mg, and chlorphenamine maleate 2mg.

Panadol C&F Cold & Cough packshot

Panadol C&F All in One

Panadol C&F All in One provides fast and effective relief against multiple cold symptoms such as: chesty cough, nasal congestion, fever, body aches, headache, sore throat.3,6-8,20,21,33,36

Key ingredients: Paracetamol 250mg, phenylephrine hydrochloride 5mg, and guaifenesin 100mg.

The Panadol range – the world’s leading cold and flu products

Cold icon


Find out more about colds.

Find out more

Patient care resources icon

Register Now

Join the Community

Click here to register

Patient resources icon

Patient resources

Download resources for your patients.

Find out more